Physiologically structured cell population dynamic models with applications to combined drug delivery optimisation in oncology

@inproceedings{Clairambault2012PhysiologicallySC,
  title={Physiologically structured cell population dynamic models with applications to combined drug delivery optimisation in oncology},
  author={Jean Clairambault and Olivier Fercoq},
  year={2012}
}
Optimising drug delivery in the general circulation targeted towards cancer cell populations, but inevitably reaching also proliferating healthy cell populations imposes to design optimised drug infusion algorithms in a dynamic way, i.e., controlling the growth of both populations simultaneously by the action of the drugs in use, wanted for cancer cells, and unwanted for toxic side effects on healthy cells. Towards this goal, we design models and methods, with optional representation of… CONTINUE READING