Physiologically distinct temporal cohorts of cortical interneurons arise from telencephalic Olig2-expressing precursors.

@article{Miyoshi2007PhysiologicallyDT,
  title={Physiologically distinct temporal cohorts of cortical interneurons arise from telencephalic Olig2-expressing precursors.},
  author={Goichi Miyoshi and Simon J B Butt and Hirohide Takebayashi and Gordon Fishell},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2007},
  volume={27 29},
  pages={
          7786-98
        }
}
Inhibitory GABAergic interneurons of the mouse neocortex are a highly heterogeneous population of neurons that originate from the ventral telencephalon and migrate tangentially up into the developing cortical plate. The majority of cortical interneurons arise from a transient embryonic structure known as the medial ganglionic eminence (MGE), but how the remarkable diversity is specified in this region is not known. We have taken a genetic fate mapping strategy to elucidate the temporal origins… CONTINUE READING

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