Physiologically based pharmacokinetic model use in risk assessment--Why being published is not enough.

@article{McLanahan2012PhysiologicallyBP,
  title={Physiologically based pharmacokinetic model use in risk assessment--Why being published is not enough.},
  author={Eva D. McLanahan and Hisham A. El-Masri and Lisa M. Sweeney and Leonid Y Kopylev and Harvey J. Clewell and John F Wambaugh and Paul Schlosser},
  journal={Toxicological sciences : an official journal of the Society of Toxicology},
  year={2012},
  volume={126 1},
  pages={5-15}
}
A panel of experts in physiologically based pharmacokinetic (PBPK) modeling and relevant quantitative methods was convened to describe and discuss model evaluation criteria, issues, and choices that arise in model application and computational tools for improving model quality for use in human health risk assessments (HHRAs). Although publication of a PBPK… CONTINUE READING