Physiological roles for G protein-regulated adenylyl cyclase isoforms: insights from knockout and overexpression studies.

@article{Sadana2009PhysiologicalRF,
  title={Physiological roles for G protein-regulated adenylyl cyclase isoforms: insights from knockout and overexpression studies.},
  author={Rachna A. Sadana and Carmen W. Dessauer},
  journal={Neuro-Signals},
  year={2009},
  volume={17 1},
  pages={5-22}
}
Cyclic AMP is a universal second messenger, produced by a family of adenylyl cyclase (AC) enzymes. The last three decades have brought a wealth of new information about the regulation of cyclic AMP production by ACs. Nine hormone-sensitive, membrane-bound AC isoforms have been identified in addition to a tenth isoform that lacks membrane spans and more closely resembles the cyanobacterial AC enzymes. New model systems for purifying and characterizing the catalytic domains of AC have led to the… CONTINUE READING
Highly Influential
This paper has highly influenced 12 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
94 Citations
199 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 94 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 199 references

Similar Papers

Loading similar papers…