Physiological role of SLC12 family members in the kidney.

@article{BazaValenti2016PhysiologicalRO,
  title={Physiological role of SLC12 family members in the kidney.},
  author={Silvana Baz{\'u}a-Valenti and Mar{\'i}a Casta{\~n}eda-Bueno and Gerardo Gamba},
  journal={American journal of physiology. Renal physiology},
  year={2016},
  volume={311 1},
  pages={F131-44}
}
The solute carrier family 12, as numbered according to Human Genome Organisation (HUGO) nomenclature, encodes the electroneutral cation-coupled chloride cotransporters that are expressed in many cells and tissues; they play key roles in important physiological events, such as cell volume regulation, modulation of the intracellular chloride concentration, and transepithelial ion transport. Most of these family members are expressed in specific regions of the nephron. The Na-K-2Cl cotransporter… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 2 times. VIEW TWEETS

Citations

Publications citing this paper.

References

Publications referenced by this paper.
Showing 1-10 of 157 references

Impaired degradation of WNK by Akt and PKA phosphorylation of KLHL3.

Biochemical and biophysical research communications • 2015
View 6 Excerpts
Highly Influenced

Dietary salt intake modulates differential splicing of the Na-K-2Cl cotransporter NKCC2.

American journal of physiology. Renal physiology • 2013
View 16 Excerpts
Highly Influenced

Quantitative phosphoproteomic analysis reveals cAMP/vasopressin-dependent signaling pathways in native renal thick ascending limb cells.

Proceedings of the National Academy of Sciences of the United States of America • 2010
View 4 Excerpts
Highly Influenced

Role of the WNK-activated SPAK kinase in regulating blood pressure

EMBO molecular medicine • 2010
View 4 Excerpts
Highly Influenced

Isoforms of renal Na-K-2Cl cotransporter NKCC2: expression and functional significance.

American journal of physiology. Renal physiology • 2008
View 16 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…