Physiological regulation of vascular permeability by endogenous glucocorticoids and active oxygen

@article{yanagui1983PhysiologicalRO,
  title={Physiological regulation of vascular permeability by endogenous glucocorticoids and active oxygen},
  author={Yoshihiko Ōyanagui},
  journal={Inflammation},
  year={1983},
  volume={7},
  pages={81-89}
}
A copper chelator, diethyldithiocarbamate (DDC), injection and adrenalectomy induce significant paw swelling by low doses of serotonin, histamine, or bradykinin, which can result in mild swelling in non-treated mice. Dexamethasone, Cu,Zn-superoxide dismutase (SOD), and hydroxyl radical scavengers suppressed the DDC-provoked edema, but only dexamethasone… CONTINUE READING