Physiological regulation of synaptic effectiveness at frog neuromuscular junctions.

  title={Physiological regulation of synaptic effectiveness at frog neuromuscular junctions.},
  author={Alan D. Grinnell and Albert A. Herrera},
  journal={The Journal of physiology},
1. Nerve terminals in two different muscles of the frog, the sartorius and cutaneous pectoris (c.p.), have been found to differ sharply in safety factor. This difference is shown to be attributable to corresponding disparities in the amount of transmitter released, without evident correlated morphological differences. 2. In Ringer containing 0.3 mM-Ca2+ and 1 mM-Mg2+, quantal content of c.p. junctions exceeded that of sartorius junctions by 3-4 times. 3. When quantal content was corrected for… CONTINUE READING

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