Physiological regulation of G protein-linked signaling.

@article{Morris1999PhysiologicalRO,
  title={Physiological regulation of G protein-linked signaling.},
  author={Andrew J. Morris and Craig C. Malbon},
  journal={Physiological reviews},
  year={1999},
  volume={79 4},
  pages={1373-430}
}
Heterotrimeric G proteins in vertebrates constitute a family molecular switches that transduce the activation of a populous group of cell-surface receptors to a group of diverse effector units. The receptors include the photopigments such as rhodopsin and prominent families such as the adrenergic, muscarinic acetylcholine, and chemokine receptors involved in regulating a broad spectrum of responses in humans. Signals from receptors are sensed by heterotrimeric G proteins and transduced to… CONTINUE READING
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