Physiological noise effects on the flip angle selection in BOLD fMRI

@article{GonzalezCastillo2011PhysiologicalNE,
  title={Physiological noise effects on the flip angle selection in BOLD fMRI},
  author={Javier Gonzalez-Castillo and Vinai Roopchansingh and Peter A. Bandettini and Jerzy Bodurka},
  journal={NeuroImage},
  year={2011},
  volume={54 4},
  pages={2764-78}
}
This work addresses the choice of imaging flip angle in blood oxygenation level dependent (BOLD) functional magnetic resonance imaging (fMRI). When noise of physiological origin becomes the dominant noise source in fMRI timeseries, it causes a nonlinear dependence of the temporal signal-to-noise ratio (TSNR) versus signal-to-noise ratio (SNR) that can be exploited to perform BOLD fMRI at angles well below the Ernst angle without any detrimental effect on our ability to detect sites of neuronal… CONTINUE READING
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