Physiological modeling of disposition of potential tumor-imaging radiopharmaceuticals in tumor-bearing mice.

Abstract

Radiopharmaceuticals have great potential in the early detection of human tumors. Three potential 99mTc-labeled platinum compounds based on cisplatin have been synthesized and tested in tumored mice. This report presents the analysis of the disposition data obtained after a single intravenous injection with an empirical, physiologically based… (More)

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