Physiological mechanisms underlying lactational amenorrhea.

  title={Physiological mechanisms underlying lactational amenorrhea.},
  author={Alan McNeilly and C. K. Tay and Anna F Glasier},
  journal={Annals of the New York Academy of Sciences},
Breastfeeding delays the resumption of normal ovarian cycles by disrupting the pattern of pulsatile release of GnRH from the hypothalamus and hence LH from the pituitary. The plasma concentrations of FSH during lactation are sufficient to induce follicle growth, but the inadequate pulsatile LH signal results in a reduced estradiol production by these follicles. When follicle growth and estradiol secretion does increase to normal, the suckling stimulus prevents the generation of a normal… CONTINUE READING
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