Physiological mechanisms of action of incretin and insulin in regulating skeletal muscle metabolism.

@article{Abdulla2014PhysiologicalMO,
  title={Physiological mechanisms of action of incretin and insulin in regulating skeletal muscle metabolism.},
  author={H. Abdulla and B. Phillips and Kenneth Smith and D. Wilkinson and P. Atherton and I. Idris},
  journal={Current diabetes reviews},
  year={2014},
  volume={10 5},
  pages={
          327-35
        }
}
Type II diabetes (T2D) is a progressive condition affecting approximately 350 million adults worldwide. Whilst skeletal muscle insulin resistance and beta-cell dysfunction are recognised causes of T2D, progressive loss of lean muscle mass (reducing surface area for glucose disposal area) in tandem with ageing-related adiposity (i.e. sarcopenic obesity) also plays an important role in driving hyperglycaemia progression. The anabolic effects of nutrition on the muscle are driven by the uptake of… Expand
Acute cocoa flavanol supplementation improves muscle macro- and microvascular but not anabolic responses to amino acids in older men.
The endogenous molecular clock orchestrates the temporal separation of substrate metabolism in skeletal muscle
Sarcopenia and frailty in older patients with diabetes mellitus
  • H. Umegaki
  • Medicine
  • Geriatrics & gerontology international
  • 2016
...
1
2
3
...