Physiological function and metabolism of free D-alanine in aquatic animals.

  title={Physiological function and metabolism of free D-alanine in aquatic animals.},
  author={Hiroki Abe and Naoko Yoshikawa and Mohammed Golam Sarower and Shigeru Okada},
  journal={Biological & pharmaceutical bulletin},
  volume={28 9},
Aquatic crustaceans and some bivalve mollusks contain a large amount of free D-alanine (up to 100 mumol/g wet wt.) in their tissues. Under high salinity stress, crustaceans and bivalve mollusks largely accumulate D- and L-alanine irrespective of species examined, together with L-glutamine, L-proline, and glycine of which increases are species dependent. These data indicate that D-alanine is one of the major compatible osmolytes responsible for the intracellular isosmotic regulation in the… CONTINUE READING
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