Physiological evolution of the renin-angiotensin system.

  title={Physiological evolution of the renin-angiotensin system.},
  author={Hayato Nishimura},
  journal={Japanese heart journal},
  volume={19 5},
The renin-angiotensin system (RAS) in mammals may participate in the controls of blood pressure and aldosterone secretion, and possibly in the regulation of renal function. It has been shown that renin release is controlled by:1) two intrarenal receptors, the renal arteriolar receptor and the macula densa; 2) the sympathetic nervous system; and 3) several humoral agents. Recent studies indicate interrelations between the RAS and renal prostaglandins and the kallikrein-kinin system. Comparative… CONTINUE READING