Physiological evidence for ionotropic and metabotropic glutamate receptors in rat taste cells.

@article{Lin1999PhysiologicalEF,
  title={Physiological evidence for ionotropic and metabotropic glutamate receptors in rat taste cells.},
  author={Wei Lin and Sue C Kinnamon},
  journal={Journal of neurophysiology},
  year={1999},
  volume={82 5},
  pages={2061-9}
}
Monosodium glutamate (MSG) elicits a unique taste in humans called umami. Recent molecular studies suggest that glutamate receptors similar to those in brain are present in taste cells, but their precise role in taste transduction remains to be elucidated. We used giga-seal whole cell recording to examine the effects of MSG and glutamate receptor agonists on membrane properties of taste cells from rat fungiform papillae. MSG (1 mM) induced three subsets of responses in cells voltage-clamped at… CONTINUE READING