Physiological effects of fenpropimorph on wild-type Saccharomyces cerevisiae and fenpropimorph-resistant mutants.

  title={Physiological effects of fenpropimorph on wild-type Saccharomyces cerevisiae and fenpropimorph-resistant mutants.},
  author={R. Lorenz and L. Parks},
  journal={Antimicrobial Agents and Chemotherapy},
  pages={1532 - 1537}
  • R. Lorenz, L. Parks
  • Published 1991
  • Biology, Medicine
  • Antimicrobial Agents and Chemotherapy
  • Fenpropimorph-resistant mutants of Saccharomyces cerevisiae were isolated by a gradient selection procedure. The mutants were cross-resistant to other morpholines (fenpropidin, dodemorph, tridemorph) and 15-azasterol, but were susceptible to azoles (miconazole, clotrimazole, ketoconazole) and nystatin. In the absence of fenpropimorph, the major sterol produced by the mutants and the parental strain was ergosterol. In the presence of fenpropimorph, ignosterol (ergosta-8,14-dien-3 beta-ol) was… CONTINUE READING
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