Physiological effects and bioconcentration of triclosan on amphibian larvae.

  title={Physiological effects and bioconcentration of triclosan on amphibian larvae.},
  author={Nicole M Palenske and Gopinath C Nallani and Edward M Dzialowski},
  journal={Comparative biochemistry and physiology. Toxicology & pharmacology : CBP},
  volume={152 2},
We examined the acute effects of triclosan (TCS) exposure, a common antimicrobial found as a contaminant in the field, on survival and physiology of amphibian larvae. LC50 values were determined after 96h for North American larval species: Acris crepitans blanchardii, Bufo woodhousii woodhousii, Rana sphenocephala, and for a developmental model: Xenopus laevis. Amphibian larvae were most sensitive to TCS exposure during early development based upon 96-h LC50 values. Heart rates for X. laevis… CONTINUE READING