Physiological correlation between lactate dehydrogenase genotype and haemoglobin function in killifish

@article{Powers1979PhysiologicalCB,
  title={Physiological correlation between lactate dehydrogenase genotype and haemoglobin function in killifish},
  author={Dennis A. Powers and G S Greaney and Allen R. Place},
  journal={Nature},
  year={1979},
  volume={277},
  pages={240-241}
}
ERYTHROCYTE organic phosphate concentration is known to be an heritable trait in both humans and rats1–3. In humans this trait has been correlated with genetic variability of both pyruvate kinase and hexokinase2. However, similar phenomena have not been reported in lower vertebrates. During our studies on the allosteric regulation of fish haemoglobins by ATP (ref. 4) we observed significant variability in red cell ATP concentrations among individuals of the killifish Fundulus heteroclitus, and… CONTINUE READING