Physiological consequences of DnaK and DnaJ overproduction in Escherichia coli.

Abstract

The physiological consequences of molecular chaperone overproduction in Escherichia coli are presented. Constitutive overproduction of DnaK from a multicopy plasmid containing large chromosomal fragments spanning the dnaK region resulted in plasmid instability. Co-overproduction of DnaJ with DnaK stabilized plasmid levels. To examine the effects of altered… (More)

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@article{Blum1992PhysiologicalCO, title={Physiological consequences of DnaK and DnaJ overproduction in Escherichia coli.}, author={Paul Blum and J. Ory and J C Bauernfeind and Janet Krska}, journal={Journal of bacteriology}, year={1992}, volume={174 22}, pages={7436-44} }