Physiological cardiac reserve: development of a non-invasive method and first estimates in man.

@article{Cooke1998PhysiologicalCR,
  title={Physiological cardiac reserve: development of a non-invasive method and first estimates in man.},
  author={George Alastair Cooke and Paul Marshall and J K al-Timman and David J Wright and Rebecca L Riley and Roger Hainsworth and L. B. Tan},
  journal={Heart},
  year={1998},
  volume={79 3},
  pages={289-94}
}
OBJECTIVE To investigate whether physiological cardiac reserve can be measured in man without invasive procedures and whether it is a major determinant of exercise capacity. DESIGN Development of method of measurement and an observational study. SETTING A regional cardiothoracic centre. SUBJECTS 70 subjects with a wide range of cardiac function, from heart failure patients to athletes. METHODS Subjects underwent treadmill, symptom limited cardiopulmonary exercise tests to measure… CONTINUE READING
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