Physiological basis for conservation of the signal recognition particle targeting pathway in Escherichia coli.

@article{Bernstein2001PhysiologicalBF,
  title={Physiological basis for conservation of the signal recognition particle targeting pathway in Escherichia coli.},
  author={Harris D Bernstein and Janine B Hyndman},
  journal={Journal of bacteriology},
  year={2001},
  volume={183 7},
  pages={2187-97}
}
The Escherichia coli signal recognition particle (SRP) is a ribonucleoprotein complex that targets nascent inner membrane proteins (IMPs) to transport sites in the inner membrane (IM). Since SRP depletion only partially inhibits IMP insertion under some growth conditions, however, it is not clear why the particle is absolutely essential for viability… CONTINUE READING