Physiological basis and pharmacology of motion sickness: an update

@article{Yates1998PhysiologicalBA,
  title={Physiological basis and pharmacology of motion sickness: an update},
  author={Bill J. Yates and A. D. Miller and James B. Lucot},
  journal={Brain Research Bulletin},
  year={1998},
  volume={47},
  pages={395-406}
}

The neural basis of motion sickness.

TLDR
The source of the conflicts that cause the body to generate the autonomic signs and symptoms that constitute motion sickness are reviewed and a summary of the experimental data that have led to an understanding of how motion sickness is generated and can be controlled are provided.

Integration of vestibular and emetic gastrointestinal signals that produce nausea and vomiting: potential contributions to motion sickness

TLDR
Additional neurophysiologic studies, particularly those conducted in conscious animals, will be crucial to discern the integrative processes in the brain stem that result in emesis, as much is left to be learned.

Brainstem processing of vestibular sensory exafference: implications for motion sickness etiology

TLDR
It is proposed that conditions producing persistent activity of vestibular “sensory conflict” neurons, or their targets, stimulate nearby brainstem emetic centers—via an as yet unidentified mechanism.

Neural substrate for motion sickness: Involvement of the limbic system

TLDR
Involvement of the amygdala may explain some characteristic features of motion sickness, such as its diversity of signs ranging from sympathetic to parasympathetic, and its conditioned occurrence where by some susceptible persons become sick even in motionless vehicles.

Motion sickness: more than nausea and vomiting

TLDR
Substantial progress is being made in identifying the physiological mechanisms underlying the evocation of nausea, vomiting, and anxiety, and a comprehensive understanding of motion sickness may soon be attainable.

The Neurophysiology and Treatment of Motion Sickness.

TLDR
The various types of motion sickness can be treated with general measures to lessen the intersensory conflict, behavioral changes, and drugs.

Processing of vestibular inputs by the medullary lateral tegmental field of conscious cats: implications for generation of motion sickness

TLDR
Findings show that higher centers of the brain that are removed during decerebration regulate the labyrinthine inputs relayed to the LTF, either by gating connections in the brainstem or by conveying vestibular inputs directly to the region.

Motion sickness: A negative reinforcement model

  • B. Bowins
  • Psychology, Biology
    Brain Research Bulletin
  • 2010

The Physiology of Vomiting

TLDR
Although vomiting is useful to avoid food poisoning, it is maladaptive in numerous clinical conditions, including treatments with cytotoxic cancer chemotherapy agents, inhalational anesthesia for surgery, and opioids for pain control; vomiting is also prominent in chronic diseases, such as diabetic gastroparesis and cyclic vomiting syndrome.
...

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...