Physiological background of the loss of fractal heart rate dynamics.

  title={Physiological background of the loss of fractal heart rate dynamics.},
  author={Mikko Tulppo and Antti M Kiviniemi and Arto J. Hautala and Mika Kallio and Tapio Sepp{\"a}nen and Timo Heikki M{\"a}kikallio and Heikki Huikuri},
  volume={112 3},
BACKGROUND Altered fractal heart rate (HR) dynamics occur during various disease states, but the physiological background of abnormal fractal HR behavior is not well known. We tested the hypothesis that the fractal organization of human HR dynamics is determined by the balance between sympathetic and vagal outflow. METHODS AND RESULTS A short-term fractal scaling exponent (alpha1) of HR dynamics, analyzed by the detrended fluctuation analysis (DFA) method, and the high-frequency (HF) and low… CONTINUE READING
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