Physiological and pharmacological manipulations with light flashes.

  title={Physiological and pharmacological manipulations with light flashes.},
  author={Henry A. Lester and Jeanne M Nerbonne},
  journal={Annual review of biophysics and bioengineering},
In the experiments described here, a physiological measurement is made while photochemical procedures are employed to alter (a) the concentration of a ligand near membranes or proteins or (b) the structure of the ligand-receptor complexes. Because photochemical reactions often provide the quickest way to produce such chemical perturbations, we emphasize the kinetic information that such experiments have yielded. This information requires a suitably rapid physiological measurement, usually an… CONTINUE READING

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