Physiological and pharmacological investigations of small intestinal peristalsis

Abstract

1. Research Plan and Method ..................................101 2. Physiological experiments on distension-induced peristalsis guinea pig small intestine .................103 A. Preparation phase ............................................103 B. Emptying phase ..............................................106 C. Peristalis and Tone ..........................................108 3. Considerations on the comparative physiology of peristalsis in hollow organs ..........................111 4. Distension peristalsis in small intestines of other mammals ..................................................113 5. Comparative pharmacological investigations of small intestinal peristalsis ..................................113 A. Influence of the osmotic pressure ..................114 B. Effects of Pilocarpine, Physostigmine and Nicotine ........................................................116 C. Effects of Cocaine, Atropine and Opium alkaloid .........................................................118 D. Addictive or synergistic effects of Opium alkaloid .........................................................126 6. Summary of the Results .......................................130 7. Translator Notes ...................................................131 8. References ............................................................132 Research Plan and Method ..................................101 Physiological experiments on distension-induced peristalsis guinea pig small intestine .................103 A. Preparation phase ............................................103 B. Emptying phase ..............................................106 C. Peristalis and Tone ..........................................108 Preparation phase ............................................103 Emptying phase ..............................................106 Peristalis and Tone ..........................................108 Considerations on the comparative physiology of peristalsis in hollow organs ..........................111 Distension peristalsis in small intestines of other mammals ..................................................113 Comparative pharmacological investigations of small intestinal peristalsis ..................................113 A. Influence of the osmotic pressure ..................114 B. Effects of Pilocarpine, Physostigmine and Nicotine ........................................................116 C. Effects of Cocaine, Atropine and Opium alkaloid .........................................................118 D. Addictive or synergistic effects of Opium alkaloid .........................................................126 Influence of the osmotic pressure ..................114 Effects of Pilocarpine, Physostigmine and Nicotine ........................................................116 Effects of Cocaine, Atropine and Opium alkaloid .........................................................118 Addictive or synergistic effects of Opium alkaloid .........................................................126 Summary of the Results .......................................130 Translator Notes ...................................................131 References ............................................................132

DOI: 10.1007/s00210-006-0052-7

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@article{Trendelenburg2006PhysiologicalAP, title={Physiological and pharmacological investigations of small intestinal peristalsis}, author={Paul Trendelenburg}, journal={Naunyn-Schmiedeberg's Archives of Pharmacology}, year={2006}, volume={373}, pages={101-133} }