Physiological and Microfluorometric Studies of Reduction and Clearance of Retinal in Bleached Rod Photoreceptors

@article{Tsina2004PhysiologicalAM,
  title={Physiological and Microfluorometric Studies of Reduction and Clearance of Retinal in Bleached Rod Photoreceptors},
  author={Efthymia K Tsina and Chunhe Chen and Yiannis Koutalos and Petri Ala-Laurila and Marco Tsacopoulos and Barbara N Wiggert and Rosalie K. Crouch and M Carter Cornwall},
  journal={The Journal of General Physiology},
  year={2004},
  volume={124},
  pages={429 - 443}
}
The visual cycle comprises a sequence of reactions that regenerate the visual pigment in photoreceptors during dark adaptation, starting with the reduction of all-trans retinal to all-trans retinol and its clearance from photoreceptors. We have followed the reduction of retinal and clearance of retinol within bleached outer segments of red rods isolated from salamander retina by measuring its intrinsic fluorescence. Following exposure to a bright light (bleach), increasing fluorescence… CONTINUE READING