Physiological and Evolutionary Theories of Dominance

@article{Wright1934PhysiologicalAE,
  title={Physiological and Evolutionary Theories of Dominance},
  author={Sewall Wright},
  journal={The American Naturalist},
  year={1934},
  volume={68},
  pages={24 - 53}
}
  • S. Wright
  • Published 1 January 1934
  • Biology
  • The American Naturalist
INTRODUCTION MENDEL found that one member of each of his seven pairs of alternative characters of the pea reappeared in the first cross-bred generation to the complete or nearly complete exclusion of the other. Although lie attributed 1o great importance to this himself, there was some tendency, following the rediscovery in 1900, to consider a law of dominance as oiie of thle fundamental principles of heredity. It has long fallen from this estate and it has beeii questioned whether careful… 

Linkage and the evolution of dominance

TLDR
The theory of Fisher that the phenomenon of dominance is a result of natural selection of modifying genes requires some reconsideration, since several formulae used by Fisher are false, and hence the conclusions based on them are false.

The evolution and nature of dominance.

  • J. Crosby
  • Biology
    Journal of theoretical biology
  • 1963

ON THE ROLES OF DIRECTED AND RANDOM CHANGES IN GENE FREQUENCY IN THE GENETICS OF POPULATIONS

  • S. Wright
  • Geology
    Evolution; international journal of organic evolution
  • 1948
Science has largely advanced by the analytic procedure of isolating the effects of single factors in carefully controlled experiments. The task of science is not complete, however, without synthesis:

Dominance Modifiers of Scute in Drosophila Pseudoobscura.

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Investigation of the manifestatioi of the gene Scute in heterozygotes with various different strains of race A as well as race B and hoped that some experimental evidence bearing on the above problems might be obtained in Drosophila pseudoobscura.

Pleiotropy in the Evolution of Structural Reduction and of Dominance

TLDR
The hypothesis of almost universal pleiotropy, which I accepted, was the basis for both my primary objection to Fisher's hypothesis and my interpretation of structural reduction in evolution.

The evolution of dominance

TLDR
The evolution of dominance has been subject to intensive debate since Fisher first argued that modifiers would be selected for if they made wild-type alleles more dominant over mutant alleles, and there is reason to believe that dominance relationships have been moulded by natural selection to some extent.

THE EVOLUTION OF DOMINANCE: A THEORY WHOSE TIME HAS PASSED?

TLDR
It is concluded that the evolution of dominance by the selection of modifiers of the phenotypes of deleterious mutations has a role as the explanation of the dominance found in many cases of selection through visual predation and that the selection mechanism long claimed to be ineffective will be effective under certain special conditions that may be different from those Fisher proposed.

LATENT NEOMORPHS AND THE EVOLUTION OF DOMINANCE

  • T. G. Gregg
  • Biology
    Evolution; international journal of organic evolution
  • 1967
TLDR
This concept is an extension of Fisher's more general notion that the initial occurrences of new mutations were intermediate in dominance and that through time they became recessive through selection of modifiers and led to the concept that a reversal of this process could result in changing a gene from a recessive to a dominant state by selection for modifiers.

Fitness Landscapes: An Alternative Theory for the Dominance of Mutation

TLDR
This article shows that under a very broad range of conditions (and environments), the average dominance of mutation of small effects should be approximately one-quarter as long as adaptation of organisms to their environment can be well described by stabilizing selection on an arbitrary set of phenotypic traits, and provides possible extension of the theory for this class of mutations.
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