Physiological aging and penile erectile function: a study in the rat.

@article{Calabr1996PhysiologicalAA,
  title={Physiological aging and penile erectile function: a study in the rat.},
  author={Antonio Calabr{\`o} and Giuseppe F. Italiano and Edoardo Stefano Pescatori and Angela Helena Marin and Orsini Gaetano and Giuseppe Abatangelo and Federico Pagano},
  journal={European urology},
  year={1996},
  volume={29 2},
  pages={
          240-4
        }
}
Erectile function of adult (8-month-old) and aged (27-month-old) rats was investigated by in vivo and in vitro assays. Reflexogenic tonic erections were evoked in vivo by electrostimulation of the dorsal nerve of the penis. Aged rats developed tendentially low intracavernosal pressures, and the kinetics of erection and detumescence were significantly lower than in adult animals. The erectile tissue isolated from aged rats exhibited poor response to papaverine. When precontracted with… CONTINUE READING

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