Physiological adaptation of an Antarctic Na+/K+-ATPase to the cold.

  title={Physiological adaptation of an Antarctic Na+/K+-ATPase to the cold.},
  author={Gaddiel Galarza-Mu{\~n}oz and Sonia I Soto-Morales and Miguel Holmgren and Joshua J C Rosenthal},
  journal={The Journal of experimental biology},
  volume={214 Pt 13},
Because enzymatic activity is strongly suppressed by the cold, polar poikilotherms face significant adaptive challenges. For example, at 0°C the catalytic activity of a typical enzyme from a temperate organism is reduced by more than 90%. Enzymes embedded in the plasma membrane, such as the Na(+)/K(+)-ATPase, may be even more susceptible to the cold because of thermal effects on the lipid bilayer. Accordingly, adaptive changes in response to the cold may include adjustments to the enzyme or the… CONTINUE READING