Physiological Modulation of the Reverse Cholesterol Transport Pathway in Vivo Reija Silvennoinen

  • Miriam-Lee Rueckert, Docent Pia Siljander, Elina Ikonen, Docent Katarina Öörni, Docent Anna-Liisa Levonen
  • Published 2015

Abstract

Atherosclerosis is a progressive disease characterized by the appearance of inflamed lesions in the arterial wall. The main component of an atherosclerotic lesion is a cholesterol-filled macrophage (a foam cell). In addition, the inflamed intima contains numerous mast cells which, upon activation, acutely secrete serine proteases and other mediators that… (More)

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