Physiological, hormonal, and behavioral responses to a single fentanyl dose in intubated and ventilated preterm neonates.

OBJECTIVE To study the responses of ventilated preterm neonates to a single dose of opioid. STUDY DESIGN In a randomized, double-blind, controlled trial, 22 mechanically ventilated preterm infants (< or = 32 weeks) were observed before medication and at 30 and 60 minutes after administration of fentanyl (3 micrograms/kg) or placebo. Heart rate, blood… CONTINUE READING