Physiologic principles and clinical sequelae of cardiopulmonary bypass.

@article{Weiland1986PhysiologicPA,
  title={Physiologic principles and clinical sequelae of cardiopulmonary bypass.},
  author={Allan Weiland and William E. Walker},
  journal={Heart & lung : the journal of critical care},
  year={1986},
  volume={15 1},
  pages={34-9}
}
CPB has been a key element in the safe and effective practice of cardiac surgery since its inception more than 30 years ago. Refinements in the apparatus, methods of tissue preservation, and innovations in technique have lowered the morbidity and mortality rates from these procedures. Despite these factors, the pump-oxygenator apparatus itself and the processes of hemodilution, hypothermia, and anticoagulation, which are intrinsic to its operation, effect temporary physiologic derangements in… CONTINUE READING

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