Physiologic levels of epidermal growth factor in saliva stimulate cell migration of an oral epithelial cell line, HO-1-N-1.

@article{Ohshima2002PhysiologicLO,
  title={Physiologic levels of epidermal growth factor in saliva stimulate cell migration of an oral epithelial cell line, HO-1-N-1.},
  author={Mitsuhiro Ohshima and Masashi Sato and Masako Ishikawa and Masao Maeno and Kichibee Otsuka},
  journal={European journal of oral sciences},
  year={2002},
  volume={110 2},
  pages={130-6}
}
An oral epithelial cell line derived from buccal mucosa squamous cell carcinoma, HO-1-N-1, was used to elucidate the role of epidermal growth factor (EGF) in saliva on wound healing of the oral mucosa. The effects of EGF on DNA synthesis, and cell migration was studied and the related signal transduction pathways examined. DNA synthesis by HO-1-N-1 cells… CONTINUE READING