• Biology, Medicine
  • Published in
    Frontiers in bioscience : a…
    1998
  • DOI:10.2741/A336

Physiologic importance of protein phosphatase inhibitors.

@article{Oliver1998PhysiologicIO,
  title={Physiologic importance of protein phosphatase inhibitors.},
  author={Carey J. Oliver and Shirish Shenolikar},
  journal={Frontiers in bioscience : a journal and virtual library},
  year={1998},
  volume={3},
  pages={
          D961-72
        }
}
Reversible protein phosphorylation is an important mode of regulation of cellular processes. While earlier studies focused on protein kinases, it is now apparent that protein phosphatases play an equally integral role in the control of cellular phosphoproteins. This review examines the role played by endogenous inhibitors of three major protein serine/threonine phosphatases, PP1, PP2A and PP2B in the control of cell physiology. The discussion highlights novel paradigms for signal transduction… CONTINUE READING

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