Physiologic effects of normal-or low-oxygen-affinity red cells in hypoxic baboons.

@article{Spector1977PhysiologicEO,
  title={Physiologic effects of normal-or low-oxygen-affinity red cells in hypoxic baboons.},
  author={Jesse I. Spector and Charles G Zaroulis and Linda E Pivacek and Charles P. Emerson and C. Robert Valeri},
  journal={The American journal of physiology},
  year={1977},
  volume={232 1},
  pages={H79-84}
}
Baboons were bled one-third their red cell mass and were given homologous transfusions of red blood cells to restore the red cell volume. One group of baboons received red blood cells with a normal 2,3-diphosphoglycerate 2,3-DPG) level and normal affinity for oxygen, and in this group the 2,3-DPG level after transfusion was normal. The other group received red blood cells with a 160% of normal 2,3-DPG level and decreased affinity for oxygen, and in this group the 2,3-DPG level after transfusion… CONTINUE READING
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