Physiologic and pathologic oscillations

  title={Physiologic and pathologic oscillations},
  author={Yehezkel Ben-Ari},
  journal={Trends in Neurosciences},
  • Y. Ben-Ari
  • Published 1 July 2007
  • Psychology
  • Trends in Neurosciences
This special issue of Trends in Neurosciences is dedicated to the INMED/TINS meeting held in La Ciotat, France, in September, 2006, which focussed on physiological and pathological oscillations in the brain.The mechanisms that translate voltage- and transmitter-gated channel activity into behaviour rely on the generation of specific types of neural oscillation. Oscillatory electrical activity occurs in the brain when groups of neurons synchronize their firing activity. These oscillations are… 
The Dependence of Spike Field Coherence on Expected Intensity
It is demonstrated that theoretical spike-field coherence for a broad class of spiking models depends on the expected rate of spiker activity, and intensity field coherence is a rate-independent measure and a candidate on which to base the appropriate statistical inference of spike field synchrony.
Integrating Artificial Intelligence with Real-time Intracranial EEG Monitoring to Automate Interictal Identification of Seizure Onset Zones in Focal Epilepsy
This report reports an artificial intelligence-based approach for combining multiple interictal electrophysiological biomarkers and their temporal characteristics as a way of accounting for the above barriers and shows that it can reliably identify seizure onset zones in a study cohort of 82 patients who underwent evaluation for drug-resistant epilepsy.


Are corticothalamic ‘up’ states fragments of wakefulness?
Electrophysiological and computational evidence from the cortex and thalamus now indicates that slow-oscillation 'up' states and the 'activated' state of wakefulness are remarkably similar dynamic entities.
Human gamma-frequency oscillations associated with attention and memory
Recent findings demonstrating human gamma-frequency activity associated with attention and memory in both sensory and non-sensory areas are discussed.
Role of GABAergic inhibition in hippocampal network oscillations
The mechanisms by which synaptic inhibition can control the precise timing of spike generation are reviewed, by way of effects of GABAergic events on membrane conductance ('shunting' inhibition) and membrane potential ('hyperpolarizing' inhibition).
The gamma cycle
Evidence is reviewed suggesting that the resulting rhythmic network inhibition interacts with excitatory input to pyramidal cells such that the more excited cells fire earlier in the gamma cycle, enabling transmission and read out of amplitude information within a single gamma cycle without requiring rate integration.
Thalamic synchrony and dynamic regulation of global forebrain oscillations
Recent studies show that regulation of excitability in the reticular nucleus leads to dynamical modulation of the state of the thalamic circuit and provide a basis for explaining how a variety of unrelated genetic alterations might lead to the spike-wave phenotype.
Analysis of dynamic brain oscillations: methodological advances
This review focuses on up-to-date recording techniques for measurement of network oscillations and new analysis tools for their quantitative assessment, and emphasizes how these methods can be applied, what property might be inferred from neuronal signals and potentially productive future directions.
Pathological synchronization in Parkinson's disease: networks, models and treatments
This review is based on presentations at the annual INMED/TINS symposium, Physiogenic and pathogenic oscillations: the beauty and the beast, based on work using tissue slice preparations, animal models and in humans with Parkinson's disease.
Network and intrinsic cellular mechanisms underlying theta phase precession of hippocampal neurons
A hybrid model, in which the look-ahead phenomenon implied by phase precession originates in superficial entorhinal cortex by some form of interference mechanism and is enhanced in the hippocampus proper by asymmetric synaptic plasticity during sequence encoding, seems to be consistent with available data, but as yet there is no fully satisfactory theoretical account of this phenomenon.