Physiologic and histologic changes in near-term fetal lambs exposed to asphyxia by partial umbilical cord occlusion.

@article{Ikeda1998PhysiologicAH,
  title={Physiologic and histologic changes in near-term fetal lambs exposed to asphyxia by partial umbilical cord occlusion.},
  author={Taichi Ikeda and Yuji Murata and Edward J. Quilligan and Ben H. Choi and Julian T. Parer and Shigehiro Doi and Seok Don Park},
  journal={American journal of obstetrics and gynecology},
  year={1998},
  volume={178 1 Pt 1},
  pages={24-32}
}
OBJECTIVES Our purpose was to characterize the histologic changes in the asphyxiated fetal lamb brain and to correlate the severity of these changes with fetal physiologic parameters during and after asphyxia. STUDY DESIGN Seventeen near-term fetuses were used for analysis: control group without manipulation (n = 4, 132 +/- 1.1 days of gestation at autopsy, mean +/- SEM), sham-asphyxia control group (n = 3, 132 +/- 1.3 days), and asphyxiated group, which successfully survived 72 hours after… CONTINUE READING

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