Physiologic abnormalities and outcome from acute disease. Evidence for a predictable relationship.

@article{Wagner1986PhysiologicAA,
  title={Physiologic abnormalities and outcome from acute disease. Evidence for a predictable relationship.},
  author={Douglas P. Wagner and William A. Knaus and ElizabethA. Draper},
  journal={Archives of internal medicine},
  year={1986},
  volume={146 7},
  pages={
          1389-96
        }
}
Initial physiologic data from 1625 nonoperative patients with 18 acute life-threatening diseases treated in an intensive care unit suggest a uniform predictable relationship between acute changes in normal physiologic balance and a patient's risk of death. We found that incremental deviations from normal physiologic balance represent equivalent and predictable incremental risks to survival, regardless of the disease initiating the physiologic disturbance. The relative impact of these… CONTINUE READING
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