Physiochemical studies on achatininH, a novel sialic acid-binding lectin.

@article{Mandal1989PhysiochemicalSO,
  title={Physiochemical studies on achatininH, a novel sialic acid-binding lectin.},
  author={C. Mandal and S. Basu},
  journal={The Biochemical journal},
  year={1989},
  volume={257 1},
  pages={
          65-71
        }
}
We have purified a sialic acid-binding lectin, achatininH, in a single step by affinity chromatography, having high affinity for 9-O-acetylneuraminic acid. The physicochemical characterization of the interaction of achatininH with bivalent metal ions and sialic acid derivatives by the use of spectrofluorimetry, spectropolarimetry and precipitin reaction is reported. From fluorescence quenching studies the binding of Ca2+ (Ka = 251 +/- 9 M-1) and of Mn2+ (Ka = 86 +/- 5 M-1) was found to be weak… Expand
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