Physicomechanical properties of biodegradable poly(D,L-lactide) and poly(D,L-lactide-co-glycolide) films in the dry and wet states.

@article{Kranz2000PhysicomechanicalPO,
  title={Physicomechanical properties of biodegradable poly(D,L-lactide) and poly(D,L-lactide-co-glycolide) films in the dry and wet states.},
  author={Heiko Kranz and Nathalie Ubrich and Philippe Maincent and Roland A Bodmeier},
  journal={Journal of pharmaceutical sciences},
  year={2000},
  volume={89 12},
  pages={1558-66}
}
The objective of this study was to investigate the mechanical properties (% elongation and puncture strength) of poly(D,L-lactide) (PLA) and poly(D,L-lactide-co-glycolide) (PLGA) films as a function of exposure time to an aqueous medium and to correlate the mechanical properties to the degradation/erosion of the polymer as a function of the type of polymer [PLA, weight-average molecular weight (M(W)) 270,300, or PLGA 50:50, M(W) 56,500], the type of plasticizer [(triethyl citrate (TEC) or… CONTINUE READING
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