Physicomechanical Properties of Naproxen-Loaded Microparticles Prepared from Eudragit L100

  title={Physicomechanical Properties of Naproxen-Loaded Microparticles Prepared from Eudragit L100},
  author={Maryam Maghsoodi},
  journal={AAPS PharmSciTech},
Microparticles of naproxen with Eudragit L100 and Aerosil were prepared by the emulsion solvent diffusion method in order to avoid local gastrointestinal irritation, one of the major side effects of nonsteroidal anti-inflammatory drugs after oral ingestion. The process of preparation involved the use of ethanol as good solvent, dichloromethane as a bridging liquid, water as poor solvent, Aerosil as anti-adhesion agent, and sodium dodecyl sulfate to aid in the dispersion of the drug and… CONTINUE READING
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