Physicochemical effects of terpenes on organogel for transdermal drug delivery.

@article{Lim2008PhysicochemicalEO,
  title={Physicochemical effects of terpenes on organogel for transdermal drug delivery.},
  author={Perry Fung Chye Lim and Xiang Yang Liu and Lifeng Kang and Paul Chi Lui Ho and S. Y. P. Chan},
  journal={International journal of pharmaceutics},
  year={2008},
  volume={358 1-2},
  pages={102-7}
}
It is accepted that terpenes are effective penetration enhancers to promote the passage of drugs or chemicals through the human skin barrier. However the physical and chemical changes of a pharmaceutical vehicle induced by the incorporation of terpenes have not been explored. Thus, this study examines the effects of three terpenes (linalool, cineole, limonene) on the rheology and chemical stability of an organogel composed of dibutyllauroylglutamide (GP1) and propylene glycol (PG). At a given… CONTINUE READING