Physico-chemical properties of quartz from industrial manufacturing and its cytotoxic effects on alveolar macrophages: The case of green sand mould casting for iron production.

@article{diBenedetto2016PhysicochemicalPO,
  title={Physico-chemical properties of quartz from industrial manufacturing and its cytotoxic effects on alveolar macrophages: The case of green sand mould casting for iron production.},
  author={Francesco di Benedetto and Elena Gazzano and Maura Tomatis and Francesco Turci and Luca A. Pardi and Simona Bronco and Gabriele Fornaciai and Massimo Innocenti and Giordano Montegrossi and Maurizio Muniz Miranda and Alfonso Zoleo and Fabio Capacci and Bice Fubini and Dario Ghigo and Maurizio Romanelli},
  journal={Journal of hazardous materials},
  year={2016},
  volume={312},
  pages={
          18-27
        }
}
View on PubMed
iris.unito.it
7 Citations
Background Citations
1

Figures and Tables from this paper

7 Citations

A new aerosol into-supramolecular solvent microextraction for spectrophotometric determination of crystalline silica in respirable dust using multivariate optimization

Determination of crystalline silica in respirable dust upon occupational exposure for Egyptian workers

Investigating occupational exposure to crystalline silica dust at 22 factories in Egypt with different industrial activities like stone cutting, glass making, ceramic, and sand blasting shows that the exposure at each of the industrial sectors is very much higher than the current national and international limits.

Influence of Loading Quantity on the Properties of Quartz Sand Powder via Mechanical Ball Milling Method

In order to improve the utilization and added value of the Yangtze river sand, the raw materials for preparing high performance quartz sand insulating brick were investigated, the following…

Occupational exposure to dust and to fumes, work as a welder and invasive pneumococcal disease risk

Work specifically as a welder, but also occupational exposures more broadly, increase the odds for IPD, and Welders, and potentially others with relevant exposures, should be offered pneumococcal vaccination.

Cumulative occupational exposure to inorganic dust and fumes and invasive pneumococcal disease with pneumonia

Evidence is added that the risk of pneumococcal pneumonia increases with increasing cumulative exposure to dust and fumes, indicating the importance of cumulative exposure.

Ab initio study of the enantio-selective magnetic-field-induced second harmonic generation in chiral molecules.

An attempt is made to analyze the structure-property relationships of enantio-selective magnetic-field-induced second harmonic generation on a set of chiral systems, based on the results obtained for biphenyl, for prolinol and for some of their derivatives.

Respiratory exposure during the additive manufacturing of sand casting moulds

.............................................................................................................................. ix OPSOMMING…

References

SHOWING 1-10 OF 55 REFERENCES

Carbon in intimate contact with quartz reduces the biological activity of crystalline silica dusts.

None of these effects takes place when the same experiments are carried out with mechanically mixed samples, which suggests that carbon acts not just as a radical quencher but because of its association to the quartz surface.

Physicochemical properties of crystalline silica dusts and their possible implication in various biological responses.

Investigation of the effect of grinding, heating, and etching on polymorphs of silicon dioxide exhibiting different biological responses found a loss in heated quartz that was relatable to the corresponding reduction in fibrogenicity.

Free radical generation in the toxicity of inhaled mineral particles: the role of iron speciation at the surface of asbestos and silica

The radical yield attained is close to the level produced by a pure quartz dust, suggesting the presence of active sites other than iron, and selective removal of iron and silicon from the surface may account for the differences in behaviour of the two particulates.

The quartz hazard: effects of surface and matrix on inflammogenic activity.

Amelioration of quartz surface activity can occur in workplace samples of quartz and quartz samples whose surface is protected, to the extent that they have very little inflammogenic activity and display an inability to activate key subcellular pathways that lead to inflammation.

Variability of the health effects of crystalline silica: Fe speciation in industrial quartz reagents and suspended dusts—insights from XAS spectroscopy

We investigated the speciation of Fe in bulk and in suspended respirable quartz dusts coming from ceramic and iron-casting industrial processes via X-ray absorption spectroscopy, with the aim of…

The iron-related molecular toxicity mechanism of synthetic asbestos nanofibres: a model study for high-aspect-ratio nanoparticles.

The use of model solids that only differ in one property at a time appears to be the most successful approach for a molecular understanding of the physico-chemical determinants of toxicity.

Response of alveolar macrophages to in vitro exposure to freshly fractured versus aged silica dust: the ability of Prosil 28, an organosilane material, to coat silica and reduce its biological reactivity.

Data indicate that freshly ground silica is more cytotoxic and is a more potent activator of alveolar macrophages than comparably sized aged silica, and that treating dust with coating agents may substantially decrease toxicity.

Relationship between the state of the surface of four commercial quartz flours and their biological activity in vitro and in vivo.

It is hypothesized that cellular response, and particularly macrophage activation and death, is mediated by strong interactions between silanol patches and some cell membrane components, but inhibited when the surface of the particle is modified by the presence of aluminium ions, surface carbonates and other metal contaminants.

Physicochemical determinants in the cellular responses to nanostructured amorphous silicas.

It is assumed here that full hydroxylation of a silica surface, with consequent stable coverage by water molecules, reduces/inhibits toxic behavior, and the preparation route appears thus determinant in yielding potentially toxic materials, although the smallest size does not always correspond to an increased toxicity.

In vitro genotoxicity assessment of commercial quartz flours in comparison to standard DQ12 quartz.

It is concluded that quartzes do not cause strand breaks without concomitant cell toxicity and a sufficient in vitro concentration of > 40 micrograms/cm2 can only be reached in vivo with instillation of massive doses (> 100 mg).
...