Physico-chemical properties of quartz from industrial manufacturing and its cytotoxic effects on alveolar macrophages: The case of green sand mould casting for iron production.

@article{diBenedetto2016PhysicochemicalPO,
  title={Physico-chemical properties of quartz from industrial manufacturing and its cytotoxic effects on alveolar macrophages: The case of green sand mould casting for iron production.},
  author={Francesco di Benedetto and Elena Gazzano and Maura Tomatis and Francesco Turci and Luca Pardi and Simona Bronco and Gabriele Fornaciai and Massimo Innocenti and Giordano Montegrossi and Maurizio Muniz Miranda and Alfonso Zoleo and Fabio Capacci and Bice Fubini and Dario Ghigo and Maurizio Romanelli},
  journal={Journal of hazardous materials},
  year={2016},
  volume={312},
  pages={
          18-27
        }
}
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References

SHOWING 1-10 OF 55 REFERENCES

Carbon in intimate contact with quartz reduces the biological activity of crystalline silica dusts.

None of these effects takes place when the same experiments are carried out with mechanically mixed samples, which suggests that carbon acts not just as a radical quencher but because of its association to the quartz surface.

Physicochemical properties of crystalline silica dusts and their possible implication in various biological responses.

Investigation of the effect of grinding, heating, and etching on polymorphs of silicon dioxide exhibiting different biological responses found a loss in heated quartz that was relatable to the corresponding reduction in fibrogenicity.

Free radical generation in the toxicity of inhaled mineral particles: the role of iron speciation at the surface of asbestos and silica

The radical yield attained is close to the level produced by a pure quartz dust, suggesting the presence of active sites other than iron, and selective removal of iron and silicon from the surface may account for the differences in behaviour of the two particulates.

The quartz hazard: effects of surface and matrix on inflammogenic activity.

Amelioration of quartz surface activity can occur in workplace samples of quartz and quartz samples whose surface is protected, to the extent that they have very little inflammogenic activity and display an inability to activate key subcellular pathways that lead to inflammation.

Variability of the health effects of crystalline silica: Fe speciation in industrial quartz reagents and suspended dusts—insights from XAS spectroscopy

We investigated the speciation of Fe in bulk and in suspended respirable quartz dusts coming from ceramic and iron-casting industrial processes via X-ray absorption spectroscopy, with the aim of…

The iron-related molecular toxicity mechanism of synthetic asbestos nanofibres: a model study for high-aspect-ratio nanoparticles.

The use of model solids that only differ in one property at a time appears to be the most successful approach for a molecular understanding of the physico-chemical determinants of toxicity.

Response of alveolar macrophages to in vitro exposure to freshly fractured versus aged silica dust: the ability of Prosil 28, an organosilane material, to coat silica and reduce its biological reactivity.

Data indicate that freshly ground silica is more cytotoxic and is a more potent activator of alveolar macrophages than comparably sized aged silica, and that treating dust with coating agents may substantially decrease toxicity.

Effect of impurities and associated minerals on quartz toxicity.

Intratracheal tests carried out with sands of various origins show that certain types of quartz may be only slightly toxic at first, then they progressively gain the usual toxicity of quartz in the lungs, and it is inferred that the absence of toxicity of coal-mine dust containing quartz is due to the presence of protective impurities on the surface of the quartz particles or to the inhibitory action of certain constituents.

Relationship between the state of the surface of four commercial quartz flours and their biological activity in vitro and in vivo.

It is hypothesized that cellular response, and particularly macrophage activation and death, is mediated by strong interactions between silanol patches and some cell membrane components, but inhibited when the surface of the particle is modified by the presence of aluminium ions, surface carbonates and other metal contaminants.

Freshly fractured quartz inhalation leads to enhanced lung injury and inflammation. Potential role of free radicals.

Inhalation of aged quartz increased the number of bronchoalveolar lavage cells, demonstrated histopathologic evidence of increased pulmonary infiltrates, and showed enhanced concentrations of biochemical markers of lung injury, increased lipid peroxidation, and the ability of pulmonary phagocytes to produce more oxygen radicals.
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