Physicians' reasons for not entering eligible patients in a randomized clinical trial of surgery for breast cancer.

@article{Taylor1984PhysiciansRF,
  title={Physicians' reasons for not entering eligible patients in a randomized clinical trial of surgery for breast cancer.},
  author={Kathryn M. Taylor and Richard G. Margolese and Colin L. Soskolne},
  journal={The New England journal of medicine},
  year={1984},
  volume={310 21},
  pages={1363-7}
}
We studied the reasons surgical principal investigators chose not to enter patients in a large, multicenter trial sponsored by a cooperative group. In 1976 the National Surgical Adjuvant Project for Breast and Bowel Cancers (NSABP) initiated a clinical trial to compare segmental mastectomy and postoperative radiation, or segmental mastectomy alone, with total mastectomy. Because the low rates of accrual were threatening to close the trial prematurely, we mailed a questionnaire to the 94 NSABP… CONTINUE READING

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