Physical training promotes similar effects to the blockade of angiotensin-converting enzyme on the cardiac morphology and function in old female rats subjected to premature ovarian failure

@article{Felix2017PhysicalTP,
  title={Physical training promotes similar effects to the blockade of angiotensin-converting enzyme on the cardiac morphology and function in old female rats subjected to premature ovarian failure},
  author={Ana Carolina Sanches Felix and Sabrina Graziani Veloso Dutra and Ada Clarice Gastaldi and P{\^a}mela C. Bonfim and Hugo Souza},
  journal={Experimental Gerontology},
  year={2017},
  volume={109},
  pages={90-98}
}
We investigated the effects of angiotensin-converting enzyme (ACE) inhibition and aerobic physical training on the heart of old female rats (82-wk-old) submitted to premature ovarian failure (10-wk.-old). We used different approaches: morphology and function by echocardiography, reactivity of the coronary bed and left ventricular contractibility (Langendorff Technique). Female Wistar ovariectomized (OVX) rats (n=42) were assigned to one of four groups: OVX, vehicle treated only; OVX-EM… CONTINUE READING

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