Physical training increases muscle GLUT4 protein and mRNA in patients with NIDDM.

@article{Dela1994PhysicalTI,
  title={Physical training increases muscle GLUT4 protein and mRNA in patients with NIDDM.},
  author={Flemming Dela and Thorkil Ploug and A Handberg and Lone N{\o}rgaard Petersen and Jim Stenfatt Larsen and K{\'a}ri Joensen Mikines and Henrik Galbo},
  journal={Diabetes},
  year={1994},
  volume={43 7},
  pages={
          862-5
        }
}
Patients with non-insulin-dependent diabetes mellitus (NIDDM) exhibit insulin resistance and decreased glucose transport in skeletal muscle. Total content of muscle GLUT4 protein is not affected by NIDDM, whereas GLUT4 mRNA content is reported, variously, to be unaffected or increased. Physical training is recommended in the treatment of NIDDM, but the effect of training on muscle GLUT4 protein and mRNA content is unknown. To clarify the effect of training in NIDDM, seven men with NIDDM (58… CONTINUE READING
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