Physical therapy intervention (PTI) increases plasma brain-derived neurotrophic factor (BDNF) levels in non-frail and pre-frail elderly women.

@article{Coelho2012PhysicalTI,
  title={Physical therapy intervention (PTI) increases plasma brain-derived neurotrophic factor (BDNF) levels in non-frail and pre-frail elderly women.},
  author={Fernanda Matos Coelho and Daniele Sirineu Pereira and Lygia Paccini Lustosa and Juscelio Pereira da Silva and Jo{\~a}o Marcos Domingues Dias and Ros{\^a}ngela Corr{\^e}a Dias and B{\'a}rbara Zille de Queiroz and Andrei Luiz Sales Teixeira and Mauro Martins Teixeira and Leani Souza M{\'a}ximo Pereira},
  journal={Archives of gerontology and geriatrics},
  year={2012},
  volume={54 3},
  pages={
          415-20
        }
}
Biomarkers are important factors in the identification of the frail elderly (higher risk of developing disease) and in assessing the impact of PTI. On the other hand, BDNF has been related to neuroprotection in a series of central nervous system diseases in older age. The levels of BDNF in groups of elderly women classified according to Fried phenotype (non-frail and pre-frail) were compared. We assessed the impact of a PTI on BDNF levels. A convenience sample of 48 elderly women was randomly… CONTINUE READING
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