Physical state of L-histidine after freeze-drying and long-term storage.

Abstract

Liquid samples of L-histidine of varying pH values and mixed with salt, metal ions, polysorbate 80 and sucrose have been analysed by differential scanning calorimetry to evaluate the influence of these additives on the glass transition temperature and crystallisation of L-histidine during freezing and thawing. L-Histidine solutions of varying pH were freeze… (More)

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Cite this paper

@article{Osterberg1999PhysicalSO, title={Physical state of L-histidine after freeze-drying and long-term storage.}, author={Thomas Osterberg and T Wadsten}, journal={European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences}, year={1999}, volume={8 4}, pages={301-8} }