Physical properties of dinitrosyl iron complexes with thiol-containing ligands in relation with their vasodilator activity.

@article{Vanin1996PhysicalPO,
  title={Physical properties of dinitrosyl iron complexes with thiol-containing ligands in relation with their vasodilator activity.},
  author={Anatoly Fjodorovich Vanin and R A Stukan and Eugenia B. Manukhina},
  journal={Biochimica et biophysica acta},
  year={1996},
  volume={1295 1},
  pages={5-12}
}
When studying the vasodilator activity of dinitrosyl iron complexes (DNIC) with thiol-containing ligands as NO donors, it should be taken into consideration that these complexes depending on the content of thiols in the environment can occur in either of two forms that differ by their EPR, gamma-resonance and optical characteristics and also by their vasodilator effect on isolated blood vessels. The more stable diamagnetic form appears at the ratio Fe2+:RS- = 1:2. It reversibly dissociates to… CONTINUE READING

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