Physical organization of lipids in the cell wall of Mycobacterium chelonae.

@article{Nikaido1993PhysicalOO,
  title={Physical organization of lipids in the cell wall of Mycobacterium chelonae.},
  author={Hiroshi Nikaido and Sung Han Kim and Emiko Y. Rosenberg},
  journal={Molecular microbiology},
  year={1993},
  volume={8 6},
  pages={1025-30}
}
Mycobacterial cell wall functions as an effective permeability barrier, making these bacteria resistant to most antibacterial agents. It has been assumed that this low permeability was due to the presence of a large amount of unusual lipids in the cell wall, but it was not known how these lipids are able to produce such an exceptional barrier. We report here the first experimental evidence on the physical arrangement of these lipids based on X-ray diffraction studies of purified Mycobacterium… CONTINUE READING

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